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Noonan syndrome-causing SHP2 mutants impair ERK-dependent chondrocyte differentiation during endochondral bone growth.
Tajan, Mylène; Pernin-Grandjean, Julie; Beton, Nicolas; Gennero, Isabelle; Capilla, Florence; Neel, Benjamin G; Araki, Toshiyuki; Valet, Philippe; Tauber, Maithé; Salles, Jean-Pierre; Yart, Armelle; Edouard, Thomas.
  • Tajan M; INSERM UMR 1048, Institute of Cardiovascular and Metabolic Diseases (I2MC).
  • Pernin-Grandjean J; INSERM UMR 1043, Centre of Pathophysiology of Toulouse Purpan (CPTP), University of Toulouse Paul Sabatier, Toulouse, France.
  • Beton N; INSERM UMR 1043, Centre of Pathophysiology of Toulouse Purpan (CPTP), University of Toulouse Paul Sabatier, Toulouse, France.
  • Gennero I; INSERM UMR 1043, Centre of Pathophysiology of Toulouse Purpan (CPTP), University of Toulouse Paul Sabatier, Toulouse, France.
  • Capilla F; INSERM, US006, ANEXPLO/CREFRE, Histopathology Unit, Purpan Hospital, Toulouse, France.
  • Neel BG; Laura and Isaac Perlmutter Cancer Center, NYU-Langone Medical Center, NY 10016, USA.
  • Araki T; Laura and Isaac Perlmutter Cancer Center, NYU-Langone Medical Center, NY 10016, USA.
  • Valet P; INSERM UMR 1048, Institute of Cardiovascular and Metabolic Diseases (I2MC).
  • Tauber M; INSERM UMR 1043, Centre of Pathophysiology of Toulouse Purpan (CPTP), University of Toulouse Paul Sabatier, Toulouse, France.
  • Salles JP; Pediatric Department, Endocrine, Bone Diseases, and Genetics Unit, Children's Hospital, Toulouse University Hospital, Toulouse, France.
  • Yart A; INSERM UMR 1043, Centre of Pathophysiology of Toulouse Purpan (CPTP), University of Toulouse Paul Sabatier, Toulouse, France.
  • Edouard T; Pediatric Department, Endocrine, Bone Diseases, and Genetics Unit, Children's Hospital, Toulouse University Hospital, Toulouse, France.
Hum Mol Genet ; 27(13): 2276-2289, 2018 07 01.
Article en En | MEDLINE | ID: mdl-29659837
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factor I del Crecimiento Similar a la Insulina / Condrocitos / Proteína Tirosina Fosfatasa no Receptora Tipo 11 / Síndrome de Noonan Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factor I del Crecimiento Similar a la Insulina / Condrocitos / Proteína Tirosina Fosfatasa no Receptora Tipo 11 / Síndrome de Noonan Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2018 Tipo del documento: Article