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Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival.
Choi, Jason C; Wu, Wei; Phillips, Elizabeth; Plevin, Robin; Sera, Fusako; Homma, Shunichi; Worman, Howard J.
  • Choi JC; Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.
  • Wu W; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
  • Phillips E; Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
  • Plevin R; Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.
  • Sera F; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, UK.
  • Homma S; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
  • Worman HJ; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
Hum Mol Genet ; 27(13): 2290-2305, 2018 07 01.
Article en En | MEDLINE | ID: mdl-29668927

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Tirosina Fosfatasas / Lamina Tipo A / Proteína Quinasa 3 Activada por Mitógenos / Cardiomiopatías Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Año: 2018 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Tirosina Fosfatasas / Lamina Tipo A / Proteína Quinasa 3 Activada por Mitógenos / Cardiomiopatías Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Año: 2018 Tipo del documento: Article