Transvection Goes Live-Visualizing Enhancer-Promoter Communication between Chromosomes.

Tsai, Albert; Singer, Robert H; Crocker, Justin

Tsai, Albert; Singer, Robert H; Crocker, Justin.

Tsai A; Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Singer RH; Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York, USA; Janelia Research Campus of the HHMI, Ashburn, Virginia, USA.
Crocker J; Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany. Electronic address: justin.crocker@embl.de.

Mol Cell ; 70(2): 195-196, 2018 04 19.

Article en En | MEDLINE | ID: mdl-29677489

ABSTRACT

ABSTRACT

Lim et al. (2018) use live imaging in Drosophila embryos to show that enhancers can drive transcription from promoters on another chromosome when they are in close proximity. In addition, they show that multiple promoters can access the same enhancer without competition, potentially sharing a pool of factors in a transcriptional "hub."

Asunto(s)

Drosophila/genética; Elementos de Facilitación Genéticos; Animales; Cromosomas; Proteínas de Drosophila/genética; Regiones Promotoras Genéticas

Texto completo

Imprimir

XML

PubMed Links

Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Elementos de Facilitación Genéticos / Drosophila Límite: Animals Idioma: En Año: 2018 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Search on Google