The impact of pericytes on the brain and approaches for their morphological analysis.
J Chem Neuroanat
; 91: 35-45, 2018 09.
Article
en En
| MEDLINE
| ID: mdl-29678665
ABSTRACT
The interest in investigating brain pericytes is growing due to their diverse influences on neuronal function. While numerous studies have investigated the particular properties and functions of pericytes, complex insight into their functional histology is often lacking. In this work, we review and combine the current knowledge regarding brain pericyte function in normal physiology and its role in the pathogenesis of neurodegenerative diseases and tumorigenesis. Special attention is paid to the interaction between the components of the neurovascular unit. Finally, approaches used to detect brain pericytes and the methods for generating qualitative and quantitative data to assess pericyte changes are described.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Encéfalo
/
Pericitos
Tipo de estudio:
Qualitative_research
Límite:
Animals
/
Humans
Idioma:
En
Año:
2018
Tipo del documento:
Article