Evidence of hepatitis E virus infection in specific pathogen-free rabbits in Korea.
Virus Genes
; 54(4): 587-590, 2018 Aug.
Article
en En
| MEDLINE
| ID: mdl-29691774
ABSTRACT
Rabbits are considered a new natural reservoir of hepatitis E virus (HEV). In this study, HEV infection was verified by the detection of partial genomic sequence of HEV and anti-HEV antibodies in specific pathogen-free (SPF) rabbits. HEV RNA was found in 6.4% serum and 13.5% fecal samples from 126 SPF rabbits. Anti-HEV antibodies were also detected in 4.0% of the SPF rabbits. HEV genetic sequences isolated from the rabbits were clustered into a rabbit HEV clade with other rabbit HEV isolates; they were found to be most closely related with a rabbit HEV sequence previously reported in Korea. Therefore, HEV infection should be diagnosed before conducting experiments involving SPF rabbits.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Virus de la Hepatitis E
/
Hepatitis E
/
Enfermedades de los Animales
Límite:
Animals
País como asunto:
Asia
Idioma:
En
Año:
2018
Tipo del documento:
Article