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Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice.
Beli, Eleni; Yan, Yuanqing; Moldovan, Leni; Vieira, Cristiano P; Gao, Ruli; Duan, Yaqian; Prasad, Ram; Bhatwadekar, Ashay; White, Fletcher A; Townsend, Steven D; Chan, Luisa; Ryan, Caitlin N; Morton, Daniel; Moldovan, Emil G; Chu, Fang-I; Oudit, Gavin Y; Derendorf, Hartmut; Adorini, Luciano; Wang, Xiaoxin X; Evans-Molina, Carmella; Mirmira, Raghavendra G; Boulton, Michael E; Yoder, Mervin C; Li, Qiuhong; Levi, Moshe; Busik, Julia V; Grant, Maria B.
  • Beli E; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
  • Yan Y; Department of Neurosurgery, The University of Texas Health Science Center at Houston, Houston, TX.
  • Moldovan L; Department of Surgery, Indiana University School of Medicine, Indianapolis, IN.
  • Vieira CP; Department of Ophthalmology and Visual Sciences, University of Alabama, Birmingham, AL.
  • Gao R; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX.
  • Duan Y; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN.
  • Prasad R; Department of Ophthalmology and Visual Sciences, University of Alabama, Birmingham, AL.
  • Bhatwadekar A; Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN.
  • White FA; Department of Anesthesia, Indiana University School of Medicine, Indianapolis, IN.
  • Townsend SD; Department of Chemistry, Vanderbilt University, Nashville, TN.
  • Chan L; Second Genome, Inc., San Francisco, CA.
  • Ryan CN; Second Genome, Inc., San Francisco, CA.
  • Morton D; Second Genome, Inc., San Francisco, CA.
  • Moldovan EG; Northeastern University, Boston, MA.
  • Chu FI; Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA.
  • Oudit GY; Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
  • Derendorf H; Department of Pharmaceutics, University of Florida, Gainesville, FL.
  • Adorini L; Intercept Pharmaceuticals, New York, NY.
  • Wang XX; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University, Washington, DC.
  • Evans-Molina C; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
  • Mirmira RG; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN.
  • Boulton ME; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN.
  • Yoder MC; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
  • Li Q; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN.
  • Levi M; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN.
  • Busik JV; Department of Ophthalmology and Visual Sciences, University of Alabama, Birmingham, AL.
  • Grant MB; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
Diabetes ; 67(9): 1867-1879, 2018 09.
Article en En | MEDLINE | ID: mdl-29712667
Asunto(s)
Diabetes Mellitus Tipo 2/terapia; Retinopatía Diabética/prevención & control; Disbiosis/terapia; Ayuno; Microbioma Gastrointestinal; Retina/patología; Vasos Retinianos/patología; Animales; Bacteroidetes/crecimiento & desarrollo; Bacteroidetes/inmunología; Bacteroidetes/aislamiento & purificación; Ácidos y Sales Biliares/uso terapéutico; Colon/efectos de los fármacos; Colon/inmunología; Colon/metabolismo; Colon/patología; Diabetes Mellitus Tipo 2/complicaciones; Diabetes Mellitus Tipo 2/microbiología; Diabetes Mellitus Tipo 2/patología; Retinopatía Diabética/complicaciones; Retinopatía Diabética/inmunología; Retinopatía Diabética/patología; Disbiosis/complicaciones; Disbiosis/microbiología; Disbiosis/patología; Heces/microbiología; Firmicutes/crecimiento & desarrollo; Firmicutes/inmunología; Firmicutes/aislamiento & purificación; Ganglios Sensoriales/efectos de los fármacos; Ganglios Sensoriales/inmunología; Ganglios Sensoriales/metabolismo; Ganglios Sensoriales/patología; Microbioma Gastrointestinal/efectos de los fármacos; Microbioma Gastrointestinal/inmunología; Células Caliciformes/efectos de los fármacos; Células Caliciformes/inmunología; Células Caliciformes/metabolismo; Células Caliciformes/patología; Mucosa Intestinal/efectos de los fármacos; Mucosa Intestinal/inmunología; Mucosa Intestinal/metabolismo; Mucosa Intestinal/patología; Leucocitos/efectos de los fármacos; Leucocitos/inmunología; Leucocitos/patología; Masculino; Ratones Endogámicos DBA; Ratones Mutantes; Microvasos/efectos de los fármacos; Microvasos/inmunología; Microvasos/metabolismo; Microvasos/patología; Receptores Acoplados a Proteínas G/agonistas; Receptores Acoplados a Proteínas G/metabolismo; Retina/efectos de los fármacos; Retina/inmunología
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Retina / Vasos Retinianos / Ayuno / Diabetes Mellitus Tipo 2 / Retinopatía Diabética / Disbiosis / Microbioma Gastrointestinal Tipo de estudio: Prognostic_studies Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Retina / Vasos Retinianos / Ayuno / Diabetes Mellitus Tipo 2 / Retinopatía Diabética / Disbiosis / Microbioma Gastrointestinal Tipo de estudio: Prognostic_studies Idioma: En Año: 2018 Tipo del documento: Article