Acute transverse myelitis following an opsoclonus-myoclonus syndrome: An unusual presentation.
Eur J Paediatr Neurol
; 22(5): 878-881, 2018 Sep.
Article
en En
| MEDLINE
| ID: mdl-29773357
ABSTRACT
Opso-myoclonus syndrome (OMS) is a very rare and severe condition. Ataxia, opsoclonus, myoclonus and/or behavioral and sleeping disturbances define that autoimmune disorder syndrome which is paraneoplastic or triggered by an infection. Here, we report a 3 year-old immunocompetent boy who developed an atypical OMS which was later complicated by an acute transverse myelitis. Screening for neuroblastoma was negative and extensive infectious screening revealed an active HHV-6 infection confirmed by blood and cerebrospinal fluid PCR. A parainfectious disease was suggested and immunosuppressive treatment was initiated. After 2 years of follow-up, the patient has a left leg paresia needing a splint and is otherwise normal. Transverse myelitis can be associated with parainfectious OMS and earlier immunosuppressive treatment in these cases may be useful especially in young and immunocompetent children.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Infecciones por Roseolovirus
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Síndrome de Opsoclonía-Mioclonía
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Mielitis Transversa
Límite:
Child, preschool
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Humans
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Male
Idioma:
En
Año:
2018
Tipo del documento:
Article