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Phase I study of the checkpoint kinase 1 inhibitor GDC-0575 in combination with gemcitabine in patients with refractory solid tumors.
Italiano, A; Infante, J R; Shapiro, G I; Moore, K N; LoRusso, P M; Hamilton, E; Cousin, S; Toulmonde, M; Postel-Vinay, S; Tolaney, S; Blackwood, E M; Mahrus, S; Peale, F V; Lu, X; Moein, A; Epler, J; DuPree, K; Tagen, M; Murray, E R; Schutzman, J L; Lauchle, J O; Hollebecque, A; Soria, J-C.
  • Italiano A; Early Phase Trials and Sarcoma Units, Institut Bergonié, Bordeaux, France. Electronic address: a.italiano@bordeaux.unicancer.fr.
  • Infante JR; Sarah Cannon Research Institute, Nashville; Tennessee Oncology, Nashville.
  • Shapiro GI; Early Drug Development Center; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston.
  • Moore KN; Stevenson Oklahoma Cancer Center, Oklahoma City; University of Oklahoma, Oklahoma City.
  • LoRusso PM; Smilow Cancer Center, New Haven; Yale University, New Haven, USA.
  • Hamilton E; Sarah Cannon Research Institute, Nashville; Tennessee Oncology, Nashville.
  • Cousin S; Early Phase Trials and Sarcoma Units, Institut Bergonié, Bordeaux, France.
  • Toulmonde M; Early Phase Trials and Sarcoma Units, Institut Bergonié, Bordeaux, France.
  • Postel-Vinay S; Départemement d'Innovation Thérapeutique et des Essais Précoces (DITEP), Villejuif; Gustave Roussy, Villejuif; Université Paris Saclay, Villejuif; INSERM, U981, Villejuif, France.
  • Tolaney S; Early Drug Development Center; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston.
  • Blackwood EM; Genentech, Inc., South San Francisco, USA.
  • Mahrus S; Genentech, Inc., South San Francisco, USA.
  • Peale FV; Genentech, Inc., South San Francisco, USA.
  • Lu X; Genentech, Inc., South San Francisco, USA.
  • Moein A; Genentech, Inc., South San Francisco, USA.
  • Epler J; Genentech, Inc., South San Francisco, USA.
  • DuPree K; Genentech, Inc., South San Francisco, USA.
  • Tagen M; Genentech, Inc., South San Francisco, USA.
  • Murray ER; Genentech, Inc., South San Francisco, USA.
  • Schutzman JL; Genentech, Inc., South San Francisco, USA.
  • Lauchle JO; Genentech, Inc., South San Francisco, USA.
  • Hollebecque A; Départemement d'Innovation Thérapeutique et des Essais Précoces (DITEP), Villejuif; Gustave Roussy, Villejuif; Université Paris Saclay, Villejuif.
  • Soria JC; INSERM, U981, Villejuif, France.
Ann Oncol ; 29(5): 1304-1311, 2018 05 01.
Article en En | MEDLINE | ID: mdl-29788155
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperidinas / Piridinas / Pirroles / Protocolos de Quimioterapia Combinada Antineoplásica / Desoxicitidina / Inhibidores de Proteínas Quinasas / Neoplasias Tipo de estudio: Clinical_trials Límite: Aged80 Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperidinas / Piridinas / Pirroles / Protocolos de Quimioterapia Combinada Antineoplásica / Desoxicitidina / Inhibidores de Proteínas Quinasas / Neoplasias Tipo de estudio: Clinical_trials Límite: Aged80 Idioma: En Año: 2018 Tipo del documento: Article