CRISPRCasFinder, an update of CRISRFinder, includes a portable version, enhanced performance and integrates search for Cas proteins.
Nucleic Acids Res
; 46(W1): W246-W251, 2018 07 02.
Article
en En
| MEDLINE
| ID: mdl-29790974
ABSTRACT
CRISPR (clustered regularly interspaced short palindromic repeats) arrays and their associated (Cas) proteins confer bacteria and archaea adaptive immunity against exogenous mobile genetic elements, such as phages or plasmids. CRISPRCasFinder allows the identification of both CRISPR arrays and Cas proteins. The program includes (i) an improved CRISPR array detection tool facilitating expert validation based on a rating system, (ii) prediction of CRISPR orientation and (iii) a Cas protein detection and typing tool updated to match the latest classification scheme of these systems. CRISPRCasFinder can either be used online or as a standalone tool compatible with Linux operating system. All third-party software packages employed by the program are freely available. CRISPRCasFinder is available at https//crisprcas.i2bc.paris-saclay.fr.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Programas Informáticos
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Proteínas Asociadas a CRISPR
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Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas
Idioma:
En
Año:
2018
Tipo del documento:
Article