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Highly Potent Clickable Probe for Cellular Imaging of MDM2 and Assessing Dynamic Responses to MDM2-p53 Inhibition.
Lebraud, Honorine; Noble, Richard A; Phillips, Nicole; Heam, Keisha; Castro, Juan; Zhao, Yan; Newell, David R; Lunec, John; Wedge, Stephen R; Heightman, Tom D.
  • Lebraud H; Astex Pharmaceuticals , 436 Cambridge Science Park , Cambridge CB4 0QA , United Kingdom.
  • Noble RA; Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School , Newcastle University , Framlington Place , Newcastle-upon-Tyne NE2 4HH , United Kingdom.
  • Phillips N; Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School , Newcastle University , Framlington Place , Newcastle-upon-Tyne NE2 4HH , United Kingdom.
  • Heam K; Astex Pharmaceuticals , 436 Cambridge Science Park , Cambridge CB4 0QA , United Kingdom.
  • Castro J; Astex Pharmaceuticals , 436 Cambridge Science Park , Cambridge CB4 0QA , United Kingdom.
  • Zhao Y; Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School , Newcastle University , Framlington Place , Newcastle-upon-Tyne NE2 4HH , United Kingdom.
  • Newell DR; Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School , Newcastle University , Framlington Place , Newcastle-upon-Tyne NE2 4HH , United Kingdom.
  • Lunec J; Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School , Newcastle University , Framlington Place , Newcastle-upon-Tyne NE2 4HH , United Kingdom.
  • Wedge SR; Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School , Newcastle University , Framlington Place , Newcastle-upon-Tyne NE2 4HH , United Kingdom.
  • Heightman TD; Astex Pharmaceuticals , 436 Cambridge Science Park , Cambridge CB4 0QA , United Kingdom.
Bioconjug Chem ; 29(6): 2100-2106, 2018 06 20.
Article en En | MEDLINE | ID: mdl-29851469
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirrolidinas / Compuestos de Boro / Proteína p53 Supresora de Tumor / Proteínas Proto-Oncogénicas c-mdm2 / Para-Aminobenzoatos / Colorantes Fluorescentes Límite: Humans Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirrolidinas / Compuestos de Boro / Proteína p53 Supresora de Tumor / Proteínas Proto-Oncogénicas c-mdm2 / Para-Aminobenzoatos / Colorantes Fluorescentes Límite: Humans Idioma: En Año: 2018 Tipo del documento: Article