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Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy.
Tapias, Victor; Jainuddin, Shari; Ahuja, Manuj; Stack, Cliona; Elipenahli, Ceyhan; Vignisse, Julie; Gerges, Meri; Starkova, Natalia; Xu, Hui; Starkov, Anatoly A; Bettendorff, Lucien; Hushpulian, Dmitry M; Smirnova, Natalya A; Gazaryan, Irina G; Kaidery, Navneet A; Wakade, Sushama; Calingasan, Noel Y; Thomas, Bobby; Gibson, Gary E; Dumont, Magali; Beal, M Flint.
  • Tapias V; Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Jainuddin S; Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Ahuja M; Department of Pharmacology, Toxicology and Neurology, Augusta University, Augusta, GA 30912, USA.
  • Stack C; Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Elipenahli C; Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Vignisse J; Laboratory of Neurophysiology, GIGA-Neurosciences, University of Liege, 4000 Liege, Belgium.
  • Gerges M; Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Starkova N; Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Xu H; Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Starkov AA; Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Bettendorff L; Laboratory of Neurophysiology, GIGA-Neurosciences, University of Liege, 4000 Liege, Belgium.
  • Hushpulian DM; D. Rogachev Federal Scientific and Clinical Center for Pediatric Hematology, Oncology, and Immunology, 117997 Moscow, Russia.
  • Smirnova NA; Veropharm, Abbott EPD, 115088 Moscow, Russia.
  • Gazaryan IG; D. Rogachev Federal Scientific and Clinical Center for Pediatric Hematology, Oncology, and Immunology, 117997 Moscow, Russia.
  • Kaidery NA; Department of Chemistry and Physical Sciences, Pace University, Pleasantville, NY 10570, USA.
  • Wakade S; Department of Enzymology, School of Chemistry, 119991 Moscow, Russia.
  • Calingasan NY; Department of Pharmacology, Toxicology and Neurology, Augusta University, Augusta, GA 30912, USA.
  • Thomas B; Department of Pharmacology, Toxicology and Neurology, Augusta University, Augusta, GA 30912, USA.
  • Gibson GE; Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Dumont M; Department of Pharmacology, Toxicology and Neurology, Augusta University, Augusta, GA 30912, USA.
  • Beal MF; Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
Hum Mol Genet ; 27(16): 2874-2892, 2018 08 15.
Article en En | MEDLINE | ID: mdl-29860433
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tiamina / Tauopatías / Factor 2 Relacionado con NF-E2 / Elementos de Respuesta Antioxidante / Agregación Patológica de Proteínas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tiamina / Tauopatías / Factor 2 Relacionado con NF-E2 / Elementos de Respuesta Antioxidante / Agregación Patológica de Proteínas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2018 Tipo del documento: Article