DNA methylation profiling in MEN1-related pancreatic neuroendocrine tumors reveals a potential epigenetic target for treatment.

Conemans, E B; Lodewijk, L; Moelans, C B; Offerhaus, G J A; Pieterman, C R C; Morsink, F H; Dekkers, O M; de Herder, W W; Hermus, A R; van der Horst-Schrivers, A N; Drent, M L; Bisschop, P H; Havekes, B; Brosens, L A A; Dreijerink, K M A; Borel Rinkes, I H M; Timmers, H Th M; Valk, G D; Vriens, M R

Conemans, E B; Lodewijk, L; Moelans, C B; Offerhaus, G J A; Pieterman, C R C; Morsink, F H; Dekkers, O M; de Herder, W W; Hermus, A R; van der Horst-Schrivers, A N; Drent, M L; Bisschop, P H; Havekes, B; Brosens, L A A; Dreijerink, K M A; Borel Rinkes, I H M; Timmers, H Th M; Valk, G D; Vriens, M R.

Conemans EB; Departments of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Lodewijk L; Departments of Internal Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Moelans CB; Departments of Section Endocrinology, Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands.
Offerhaus GJA; Departments of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Pieterman CRC; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.
Morsink FH; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.
Dekkers OM; Departments of Internal Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
de Herder WW; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.
Hermus AR; Departments of Endocrinology and Metabolism and Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
van der Horst-Schrivers AN; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
Drent ML; Department of Endocrinology, Radboud University Medical Center, Nijmegen, The Netherlands.
Bisschop PH; Department of Endocrinology, University Medical Center Groningen, Groningen, The Netherlands.
Havekes B; Departments of Section Endocrinology, Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands.
Brosens LAA; Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands.
Dreijerink KMA; Division of Endocrinology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.
Borel Rinkes IHM; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.
Timmers HTM; Departments of Internal Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Valk GD; Departments of Section Endocrinology, Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands.
Vriens MR; Departments of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.

Eur J Endocrinol ; 179(3): 153-160, 2018 Sep.

Article en En | MEDLINE | ID: mdl-29903750

Asunto(s)

Metilación de ADN/genética; Epigénesis Genética/genética; Neoplasia Endocrina Múltiple Tipo 1/genética; Tumores Neuroendocrinos/genética; Neoplasias Pancreáticas/genética; Regiones Promotoras Genéticas/genética; Adulto; Anciano; Anciano de 80 o más Años; Femenino; Genes Supresores de Tumor; Humanos; Masculino; Persona de Mediana Edad; Proteína Supresora de Tumores del Síndrome de Von Hippel-Lindau/genética

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Regiones Promotoras Genéticas / Tumores Neuroendocrinos / Neoplasia Endocrina Múltiple Tipo 1 / Metilación de ADN / Epigénesis Genética Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2018 Tipo del documento: Article

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