Cell clustering mediated by the adhesion protein PVRL4 is necessary for &#945;6ß4 integrin-promoted ferroptosis resistance in matrix-detached cells.

Brown, Caitlin W; Amante, John J; Mercurio, Arthur M

Cell clustering mediated by the adhesion protein PVRL4 is necessary for α6ß4 integrin-promoted ferroptosis resistance in matrix-detached cells.

Brown, Caitlin W; Amante, John J; Mercurio, Arthur M.

Brown CW; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01605.
Amante JJ; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01605.
Mercurio AM; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01605. Electronic address: arthur.mercurio@umassmed.edu.

J Biol Chem ; 293(33): 12741-12748, 2018 08 17.

Article en En | MEDLINE | ID: mdl-29934307

Asunto(s)

Apoptosis; Neoplasias de la Mama/patología; Mama/patología; Moléculas de Adhesión Celular/metabolismo; Adhesión Celular; Matriz Extracelular/metabolismo; Integrina alfa6beta4/metabolismo; Hierro/metabolismo; Mama/metabolismo; Neoplasias de la Mama/metabolismo; Agregación Celular; Células Cultivadas; Femenino; Humanos; Peroxidación de Lípido; Especies Reactivas de Oxígeno/metabolismo

Palabras clave

breast cancer; cell death; cellcell interaction; extracellular matrix; ferroptosis; glutathione peroxidase 4; integrin; lipid peroxidation

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Mama / Neoplasias de la Mama / Moléculas de Adhesión Celular / Adhesión Celular / Apoptosis / Integrina alfa6beta4 / Matriz Extracelular / Hierro Límite: Female / Humans Idioma: En Año: 2018 Tipo del documento: Article

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