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Inhibitor of intramembrane protease RseP blocks the σE response causing lethal accumulation of unfolded outer membrane proteins.
Konovalova, Anna; Grabowicz, Marcin; Balibar, Carl J; Malinverni, Juliana C; Painter, Ronald E; Riley, Daniel; Mann, Paul A; Wang, Hao; Garlisi, Charles G; Sherborne, Brad; Rigel, Nathan W; Ricci, Dante P; Black, Todd A; Roemer, Terry; Silhavy, Thomas J; Walker, Scott S.
  • Konovalova A; Department of Molecular Biology, Princeton University, Princeton, NJ 08540.
  • Grabowicz M; Department of Microbiology and Molecular Genetics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.
  • Balibar CJ; Department of Molecular Biology, Princeton University, Princeton, NJ 08540.
  • Malinverni JC; Emory Antibiotic Resistance Center, Emory University School of Medicine, Atlanta, GA 30322.
  • Painter RE; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322.
  • Riley D; Division of Infectious Disease, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322.
  • Mann PA; Merck & Co., Inc., Kenilworth, NJ 07033.
  • Wang H; Merck & Co., Inc., Kenilworth, NJ 07033.
  • Garlisi CG; Merck & Co., Inc., Kenilworth, NJ 07033.
  • Sherborne B; Merck & Co., Inc., Kenilworth, NJ 07033.
  • Rigel NW; Merck & Co., Inc., Kenilworth, NJ 07033.
  • Ricci DP; Merck & Co., Inc., Kenilworth, NJ 07033.
  • Black TA; Merck & Co., Inc., Kenilworth, NJ 07033.
  • Roemer T; Hurley Consulting Associates Ltd., Summit, NJ 07901.
  • Silhavy TJ; Merck & Co., Inc., Kenilworth, NJ 07033.
  • Walker SS; Department of Molecular Biology, Princeton University, Princeton, NJ 08540.
Proc Natl Acad Sci U S A ; 115(28): E6614-E6621, 2018 07 10.
Article en En | MEDLINE | ID: mdl-29941590
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Endopeptidasas / Proteínas de la Membrana Bacteriana Externa / Factores de Transcripción / Proteínas de Escherichia coli / Escherichia coli / Desplegamiento Proteico / Proteínas de la Membrana Tipo de estudio: Prognostic_studies Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
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PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Endopeptidasas / Proteínas de la Membrana Bacteriana Externa / Factores de Transcripción / Proteínas de Escherichia coli / Escherichia coli / Desplegamiento Proteico / Proteínas de la Membrana Tipo de estudio: Prognostic_studies Idioma: En Año: 2018 Tipo del documento: Article