Prognostic ability of quick-SOFA across different age groups of patients with suspected infection outside the intensive care unit: A cohort study.
J Crit Care
; 47: 178-184, 2018 10.
Article
en En
| MEDLINE
| ID: mdl-30005305
ABSTRACT
OBJECTIVES:
Sepsis identification in older patients is challenging. We evaluated the performance of qSOFA across different age groups of patients with suspected infection outside the intensive care unit (ICU).METHODS:
Retrospective cohort in a tertiary hospital in Brazil, from January 2016 to December 2016. Outcomes were hospital mortality, ICU admission and bacteremia. Performance of qSOFA was compared over three age groups (1) reference ≤65â¯years, (2) old 65 to 79â¯years and (3) very old ≥80â¯years.RESULTS:
There were 420 patients in the study, of which 259 (61.7%) were ≤65â¯years, 80 (19%) were 65 to 79â¯years and 81 (19.3%) were ≥80â¯years. Old and very old patients had higher qSOFA scores and lower SIRS scores. Overall, qSOFA ≥2 was associated to hospital mortality [OR (95% CI)â¯=â¯5.8 (3.3-10.4), pâ¯<â¯0.001], ICU admission [OR (95% CI)â¯=â¯2.7 (1.6-4.6), pâ¯<â¯0.001] and bacteremia [OR (95% CI)â¯=â¯3.1 (1.7-5.8), pâ¯<â¯0.001]. Those associations were stronger in old and very old patients. qSOFA and SIRS demonstrated overall AUROCs for hospital mortality of 0.72 and 0.50, respectively.CONCLUSION:
qSOFA demonstrated good overall accuracy and was more strongly associated to outcomes in old and very old patients, when compared to younger patients.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Sepsis
/
Puntuaciones en la Disfunción de Órganos
/
Unidades de Cuidados Intensivos
Tipo de estudio:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Año:
2018
Tipo del documento:
Article