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Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected mice.
Koestner, Wolfgang; Spanier, Julia; Klause, Tanja; Tegtmeyer, Pia-K; Becker, Jennifer; Herder, Vanessa; Borst, Katharina; Todt, Daniel; Lienenklaus, Stefan; Gerhauser, Ingo; Detje, Claudia N; Geffers, Robert; Langereis, Martijn A; Vondran, Florian W R; Yuan, Qinggong; van Kuppeveld, Frank J M; Ott, Michael; Staeheli, Peter; Steinmann, Eike; Baumgärtner, Wolfgang; Wacker, Frank; Kalinke, Ulrich.
  • Koestner W; Institute for Radiology, Hannover Medical School, Hannover, Germany.
  • Spanier J; Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research, Braunschweig, and the Hannover Medical School, Hannover, Germany.
  • Klause T; Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research, Braunschweig, and the Hannover Medical School, Hannover, Germany.
  • Tegtmeyer PK; Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research, Braunschweig, and the Hannover Medical School, Hannover, Germany.
  • Becker J; Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research, Braunschweig, and the Hannover Medical School, Hannover, Germany.
  • Herder V; Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research, Braunschweig, and the Hannover Medical School, Hannover, Germany.
  • Borst K; Department of Pathology, University of Veterinary Medicine Hannover, Hannover, Germany.
  • Todt D; Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research, Braunschweig, and the Hannover Medical School, Hannover, Germany.
  • Lienenklaus S; Department of Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.
  • Gerhauser I; Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research, Braunschweig, and the Hannover Medical School, Hannover, Germany.
  • Detje CN; Institute for Laboratory Animal Science and Central Animal Facility, Hannover Medical School, Hannover, Germany.
  • Geffers R; Department of Pathology, University of Veterinary Medicine Hannover, Hannover, Germany.
  • Langereis MA; Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research, Braunschweig, and the Hannover Medical School, Hannover, Germany.
  • Vondran FWR; Helmholtz Centre for Infection Research, Genome Analytics Research Group, Braunschweig, Germany.
  • Yuan Q; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
  • van Kuppeveld FJM; ReMediES, Department of General, Visceral and Transplantation Surgery, Hannover Medical School, and German Centre for Infection Research, Hannover-Braunschweig, Germany.
  • Ott M; Institute for Cell and Gene Therapy, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research, Braunschweig, and the Hannover Medical School, Hannover, Germany.
  • Staeheli P; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
  • Steinmann E; Institute for Cell and Gene Therapy, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research, Braunschweig, and the Hannover Medical School, Hannover, Germany.
  • Baumgärtner W; Institute for Virology, Medical Center University of Freiburg, Freiburg, Germany.
  • Wacker F; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Kalinke U; Department of Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.
PLoS Pathog ; 14(8): e1007235, 2018 08.
Article en En | MEDLINE | ID: mdl-30075026
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Interferón beta / Enterovirus Humano B / Infecciones por Coxsackievirus / Hepatocitos / Receptor de Interferón alfa y beta / Hígado Límite: Animals / Humans Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Interferón beta / Enterovirus Humano B / Infecciones por Coxsackievirus / Hepatocitos / Receptor de Interferón alfa y beta / Hígado Límite: Animals / Humans Idioma: En Año: 2018 Tipo del documento: Article