Highly Sensitive and Selective Colorimetric Detection of Methylmercury Based on DNA Functionalized Gold Nanoparticles.
Sensors (Basel)
; 18(8)2018 Aug 15.
Article
en En
| MEDLINE
| ID: mdl-30111699
ABSTRACT
A new colorimetric detection of methylmercury (CH3Hgâº) was developed, which was based on the surface deposition of Hg enhancing the catalytic activity of gold nanoparticles (AuNPs). The AuNPs were functionalized with a specific DNA strand (HT7) recognizing CH3Hgâº, which was used to capture and separate CH3Hg⺠by centrifugation. It was found that the CH3Hg⺠reduction resulted in the deposition of Hg onto the surface of AuNPs. As a result, the catalytic activity of the AuNPs toward the chromogenic reaction of 3,3,5,5-tetramethylbenzidine (TMB)-H2O2 was remarkably enhanced. Under optimal conditions, a limit of detection of 5.0 nM was obtained for CH3Hg⺠with a linear range of 10â»200 nM. We demonstrated that the colorimetric method was fairly simple with a low cost and can be conveniently applied to CH3Hg⺠detection in environmental samples.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Colorimetría
/
Nanopartículas del Metal
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Oro
/
Compuestos de Metilmercurio
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Año:
2018
Tipo del documento:
Article