Insects Go on a STING Operation to Tackle Intracellular Invaders.

ABSTRACT

Insect immunity to extracellular microbes relies largely on the TOLL and IMD pathways. In this issue of Immunity, Goto et al. (2018) report that the IKKß-Relish module of the IMD pathway hitches up the intracellular sensor STING to activate antiviral responses in Drosophila.