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Relationship between In Vivo CYP3A4 Activity, CYP3A5 Genotype, and Systemic Tacrolimus Metabolite/Parent Drug Ratio in Renal Transplant Recipients and Healthy Volunteers.
Vanhove, Thomas; de Jonge, Hylke; de Loor, Henriëtte; Oorts, Marlies; de Hoon, Jan; Pohanka, Anton; Annaert, Pieter; Kuypers, Dirk R J.
  • Vanhove T; Departments of Microbiology and Immunology (T.V., H.d.J., H.d.L., D.R.J.K.), Pharmaceutical and Pharmacological Sciences (J.d.H.), and Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences (M.O., P.A.), Catholic University of Leuven, Leuven, Belgium; Department of
  • de Jonge H; Departments of Microbiology and Immunology (T.V., H.d.J., H.d.L., D.R.J.K.), Pharmaceutical and Pharmacological Sciences (J.d.H.), and Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences (M.O., P.A.), Catholic University of Leuven, Leuven, Belgium; Department of
  • de Loor H; Departments of Microbiology and Immunology (T.V., H.d.J., H.d.L., D.R.J.K.), Pharmaceutical and Pharmacological Sciences (J.d.H.), and Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences (M.O., P.A.), Catholic University of Leuven, Leuven, Belgium; Department of
  • Oorts M; Departments of Microbiology and Immunology (T.V., H.d.J., H.d.L., D.R.J.K.), Pharmaceutical and Pharmacological Sciences (J.d.H.), and Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences (M.O., P.A.), Catholic University of Leuven, Leuven, Belgium; Department of
  • de Hoon J; Departments of Microbiology and Immunology (T.V., H.d.J., H.d.L., D.R.J.K.), Pharmaceutical and Pharmacological Sciences (J.d.H.), and Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences (M.O., P.A.), Catholic University of Leuven, Leuven, Belgium; Department of
  • Pohanka A; Departments of Microbiology and Immunology (T.V., H.d.J., H.d.L., D.R.J.K.), Pharmaceutical and Pharmacological Sciences (J.d.H.), and Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences (M.O., P.A.), Catholic University of Leuven, Leuven, Belgium; Department of
  • Annaert P; Departments of Microbiology and Immunology (T.V., H.d.J., H.d.L., D.R.J.K.), Pharmaceutical and Pharmacological Sciences (J.d.H.), and Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences (M.O., P.A.), Catholic University of Leuven, Leuven, Belgium; Department of
  • Kuypers DRJ; Departments of Microbiology and Immunology (T.V., H.d.J., H.d.L., D.R.J.K.), Pharmaceutical and Pharmacological Sciences (J.d.H.), and Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences (M.O., P.A.), Catholic University of Leuven, Leuven, Belgium; Department of
Drug Metab Dispos ; 46(11): 1507-1513, 2018 11.
Article en En | MEDLINE | ID: mdl-30166405
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tacrolimus / Citocromo P-450 CYP3A / Riñón Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tacrolimus / Citocromo P-450 CYP3A / Riñón Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2018 Tipo del documento: Article