MiR-637 suppresses melanoma progression through directly targeting P-REX2a and inhibiting PTEN/AKT signaling pathway.

Zhang, Jian; Liu, Wen-Li; Zhang, Lu; Ge, Rui; He, Fang; Gao, Tian-Yuan; Tian, Qiong; Mu, Xin; Chen, Li-Hong; Chen, Wei; Li, Xu

Zhang, Jian; Liu, Wen-Li; Zhang, Lu; Ge, Rui; He, Fang; Gao, Tian-Yuan; Tian, Qiong; Mu, Xin; Chen, Li-Hong; Chen, Wei; Li, Xu.

Zhang J; Department of Dermatology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, P.R. China.
Liu WL; Department of Dermatology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, P.R. China.
Zhang L; Department of Foreign Languages, Ming De College of Northwestern Polytechnical University, Xi'an 710124, Shaanxi Province, P.R. China.
Ge R; Department of Dermatology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, P.R. China.
He F; Center for Translational Medicine, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, P.R. China.
Gao TY; Department of Dermatology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, P.R. China.
Tian Q; Department of Dermatology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, P.R. China.
Mu X; Department of Dermatology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, P.R. China.
Chen LH; Department of Dermatology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, P.R. China.
Chen W; Center for Translational Medicine, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, P.R. China.
Li X; Center for Translational Medicine, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, P.R. China.

Cell Mol Biol (Noisy-le-grand) ; 64(11): 50-57, 2018 Aug 30.

Article en En | MEDLINE | ID: mdl-30213289

Asunto(s)

Factores de Intercambio de Guanina Nucleótido/metabolismo; Melanoma/metabolismo; Melanoma/patología; MicroARNs/metabolismo; Fosfohidrolasa PTEN/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Apoptosis/genética; Apoptosis/fisiología; Western Blotting; Ciclo Celular/genética; Ciclo Celular/fisiología; Línea Celular Tumoral; Proliferación Celular/genética; Proliferación Celular/fisiología; Femenino; Regulación Neoplásica de la Expresión Génica/genética; Regulación Neoplásica de la Expresión Génica/fisiología; Factores de Intercambio de Guanina Nucleótido/genética; Humanos; Técnicas In Vitro; Masculino; Melanoma/genética; MicroARNs/genética; Persona de Mediana Edad; Fosfohidrolasa PTEN/genética; Proteínas Proto-Oncogénicas c-akt/genética; Reacción en Cadena en Tiempo Real de la Polimerasa; Transducción de Señal/genética; Transducción de Señal/fisiología

Palabras clave

Apoptosis.; Melanoma; P-REX2a; Proliferation; miR-637

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Banco de datos: MEDLINE Asunto principal: Factores de Intercambio de Guanina Nucleótido / MicroARNs / Fosfohidrolasa PTEN / Proteínas Proto-Oncogénicas c-akt / Melanoma Límite: Female / Humans / Male / Middle aged Idioma: En Año: 2018 Tipo del documento: Article

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