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Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate.
Sardina, Jose Luis; Collombet, Samuel; Tian, Tian V; Gómez, Antonio; Di Stefano, Bruno; Berenguer, Clara; Brumbaugh, Justin; Stadhouders, Ralph; Segura-Morales, Carolina; Gut, Marta; Gut, Ivo G; Heath, Simon; Aranda, Sergi; Di Croce, Luciano; Hochedlinger, Konrad; Thieffry, Denis; Graf, Thomas.
  • Sardina JL; Gene Regulation, Stem Cells and Cancer Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona 08003, Spain. Electronic address: joseluis.sardina@crg.eu.
  • Collombet S; Institut de Biologie de l'Ecole Normale Supérieure (IBENS), Paris Sciences & Lettres Université, CNRS UMR8197, INSERM U1024, Paris 75005, France.
  • Tian TV; Gene Regulation, Stem Cells and Cancer Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona 08003, Spain.
  • Gómez A; Gene Regulation, Stem Cells and Cancer Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona 08003, Spain.
  • Di Stefano B; Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, USA; Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, USA; Cancer Center, Massachusetts Ge
  • Berenguer C; Gene Regulation, Stem Cells and Cancer Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona 08003, Spain.
  • Brumbaugh J; Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, USA; Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, USA; Cancer Center, Massachusetts Ge
  • Stadhouders R; Gene Regulation, Stem Cells and Cancer Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona 08003, Spain.
  • Segura-Morales C; Gene Regulation, Stem Cells and Cancer Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona 08003, Spain.
  • Gut M; Universitat Pompeu Fabra (UPF), Barcelona 08003, Spain; CNAG-CRG, Centro Nacional de Análisis Genómico, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Baldiri i Reixac 4, Barcelona 08028, Spain.
  • Gut IG; Universitat Pompeu Fabra (UPF), Barcelona 08003, Spain; CNAG-CRG, Centro Nacional de Análisis Genómico, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Baldiri i Reixac 4, Barcelona 08028, Spain.
  • Heath S; Universitat Pompeu Fabra (UPF), Barcelona 08003, Spain; CNAG-CRG, Centro Nacional de Análisis Genómico, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Baldiri i Reixac 4, Barcelona 08028, Spain.
  • Aranda S; Gene Regulation, Stem Cells and Cancer Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona 08003, Spain.
  • Di Croce L; Gene Regulation, Stem Cells and Cancer Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona 08003, Spain; Universitat Pompeu Fabra (UPF), Barcelona 08003, Spain.
  • Hochedlinger K; Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, USA; Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, USA; Cancer Center, Massachusetts Ge
  • Thieffry D; Institut de Biologie de l'Ecole Normale Supérieure (IBENS), Paris Sciences & Lettres Université, CNRS UMR8197, INSERM U1024, Paris 75005, France.
  • Graf T; Gene Regulation, Stem Cells and Cancer Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona 08003, Spain; Universitat Pompeu Fabra (UPF), Barcelona 08003, Spain. Electronic address: thomas.graf@crg.eu.
Cell Stem Cell ; 23(5): 727-741.e9, 2018 11 01.
Article en En | MEDLINE | ID: mdl-30220521
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Proteínas Proto-Oncogénicas / Elementos de Facilitación Genéticos / Metilación de ADN / Proteínas de Unión al ADN / Reprogramación Celular / Células Madre Pluripotentes Inducidas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Proteínas Proto-Oncogénicas / Elementos de Facilitación Genéticos / Metilación de ADN / Proteínas de Unión al ADN / Reprogramación Celular / Células Madre Pluripotentes Inducidas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2018 Tipo del documento: Article