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Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau.
Courade, Jean-Philippe; Angers, Rachel; Mairet-Coello, Georges; Pacico, Nathalie; Tyson, Kerry; Lightwood, Daniel; Munro, Rebecca; McMillan, David; Griffin, Robert; Baker, Terry; Starkie, Dale; Nan, Ruodan; Westwood, Marta; Mushikiwabo, Marie-Laetitia; Jung, Sophie; Odede, Geofrey; Sweeney, Berni; Popplewell, Andrew; Burgess, Gillian; Downey, Patrick; Citron, Martin.
  • Courade JP; UCB Biopharma, Chemin du Foriest, 1420, Braine l'Alleud, Belgium.
  • Angers R; UCB Biopharma, Chemin du Foriest, 1420, Braine l'Alleud, Belgium.
  • Mairet-Coello G; UCB Biopharma, Chemin du Foriest, 1420, Braine l'Alleud, Belgium.
  • Pacico N; UCB Biopharma, Chemin du Foriest, 1420, Braine l'Alleud, Belgium.
  • Tyson K; UCB Celltech, 208 Bath Rd, Slough, SL1 3WE, UK.
  • Lightwood D; UCB Celltech, 208 Bath Rd, Slough, SL1 3WE, UK.
  • Munro R; UCB Celltech, 208 Bath Rd, Slough, SL1 3WE, UK.
  • McMillan D; UCB Celltech, 208 Bath Rd, Slough, SL1 3WE, UK.
  • Griffin R; UCB Celltech, 208 Bath Rd, Slough, SL1 3WE, UK.
  • Baker T; UCB Celltech, 208 Bath Rd, Slough, SL1 3WE, UK.
  • Starkie D; UCB Celltech, 208 Bath Rd, Slough, SL1 3WE, UK.
  • Nan R; UCB Celltech, 208 Bath Rd, Slough, SL1 3WE, UK.
  • Westwood M; UCB Celltech, 208 Bath Rd, Slough, SL1 3WE, UK.
  • Mushikiwabo ML; UCB Biopharma, Chemin du Foriest, 1420, Braine l'Alleud, Belgium.
  • Jung S; UCB Biopharma, Chemin du Foriest, 1420, Braine l'Alleud, Belgium.
  • Odede G; UCB Celltech, 208 Bath Rd, Slough, SL1 3WE, UK.
  • Sweeney B; UCB Celltech, 208 Bath Rd, Slough, SL1 3WE, UK.
  • Popplewell A; UCB Celltech, 208 Bath Rd, Slough, SL1 3WE, UK.
  • Burgess G; UCB Celltech, 208 Bath Rd, Slough, SL1 3WE, UK.
  • Downey P; Vertex Pharmaceuticals, 86-88 Jubilee Avenue, Milton Park, Abingdon, Oxfordshire, OX14 4RW, UK.
  • Citron M; UCB Biopharma, Chemin du Foriest, 1420, Braine l'Alleud, Belgium. patrick.downey@ucb.com.
Acta Neuropathol ; 136(5): 729-745, 2018 11.
Article en En | MEDLINE | ID: mdl-30238240

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas tau / Anticuerpos / Epítopos Límite: Humans Idioma: En Año: 2018 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas tau / Anticuerpos / Epítopos Límite: Humans Idioma: En Año: 2018 Tipo del documento: Article