Serial profile of flow-mediated dilatation in primigravida for prediction of preeclampsia and gestational hypertension.
Hypertens Pregnancy
; 37(4): 212-219, 2018 Nov.
Article
en En
| MEDLINE
| ID: mdl-30273074
ABSTRACT
OBJECTIVE:
Assessment of endothelial dysfunction for prediction of gestational hypertension/preeclampsia (GH/PE).METHODS:
Serial assessment of flow-mediated vasodilatation (FMD) of brachial artery was done in first, second, and third trimesters, and within 6 weeks of delivery in primigravida (n = 654). Logistic regression was used to assess the predictive value of FMD for the development of GH/PE.RESULTS:
Significant fall in FMD was observed from first trimester to third trimester but decrease in FMD in GH/PE group (57%) was more marked as compared to normal (39%) (p < 0.01). FMD (third trimester) was able to predict the development of GH/PE (OR = 1.303; 95% CI 1.088-1.562; p = 0.004).CONCLUSIONS:
FMD can be used as a non-invasive marker to predict the development of GH/PE.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Preeclampsia
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Vasodilatación
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Arteria Braquial
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Hipertensión Inducida en el Embarazo
Tipo de estudio:
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
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Female
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Humans
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Pregnancy
Idioma:
En
Año:
2018
Tipo del documento:
Article