Chemoradiotherapy for Unresectable INI1-negative Chordoma in a Child.
J Pediatr Hematol Oncol
; 42(1): 65-68, 2020 01.
Article
en En
| MEDLINE
| ID: mdl-30281526
ABSTRACT
The characteristics of chordomas in children are distinct from those in adults. In particular, the prognosis of patients with INI1-negative chordoma is dismal. The standard treatment for localized chordoma, complete surgical resection with a wide margin, is seldom feasible for chordomas arising at the clivus in children, mainly due to associated complications. Therefore, other treatments for unresectable chordomas in children, including chemoradiotherapy, must be explored. Here, we report a 7-year-old girl with an INI1-negative chordoma of the clivus, who responded to conventional chemotherapy plus radiotherapy. Without surgical resection, she remains alive after 1 year and 7 months of the initial diagnosis.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias de la Columna Vertebral
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Cordoma
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Quimioradioterapia
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Child
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Female
/
Humans
Idioma:
En
Año:
2020
Tipo del documento:
Article