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Synthesis and Evaluation of Novel Ligustrazine Derivatives as Multi-Targeted Inhibitors for the Treatment of Alzheimer's Disease.
Wu, Wenhao; Liang, Xintong; Xie, Guoquan; Chen, Langdi; Liu, Weixiong; Luo, Guolin; Zhang, Peiquan; Yu, Lihong; Zheng, Xuehua; Ji, Hong; Zhang, Chao; Yi, Wei.
  • Wu W; Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, Guangdong, China. wenhao_wu@gzhmu.edu.cn.
  • Liang X; Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, Guangdong, China. kilyte18@163.com.
  • Xie G; Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, Guangdong, China. guoquanxie@163.com.
  • Chen L; Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, Guangdong, China. chenlangdi427@gmail.com.
  • Liu W; Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, Guangdong, China. 13760781141@139.com.
  • Luo G; Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, Guangdong, China. 13570203692@163.com.
  • Zhang P; Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, Guangdong, China. pqzhang@gzhmu.edu.cn.
  • Yu L; Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, Guangdong, China. ylh84@126.com.
  • Zheng X; Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, Guangdong, China. zhengxh23@gzhmu.edu.cn.
  • Ji H; Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, Guangdong, China. dljih@126.com.
  • Zhang C; Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, Guangdong, China. chao-zh@163.com.
  • Yi W; Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, Guangdong, China. yiwei@gzhmu.edu.cn.
Molecules ; 23(10)2018 Oct 05.
Article en En | MEDLINE | ID: mdl-30301153

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazinas / Inhibidores de la Colinesterasa / Enfermedad de Alzheimer / Agregación Patológica de Proteínas Límite: Humans Idioma: En Año: 2018 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazinas / Inhibidores de la Colinesterasa / Enfermedad de Alzheimer / Agregación Patológica de Proteínas Límite: Humans Idioma: En Año: 2018 Tipo del documento: Article