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Progranulin reduces insoluble TDP-43 levels, slows down axonal degeneration and prolongs survival in mutant TDP-43 mice.
Beel, Sander; Herdewyn, Sarah; Fazal, Raheem; De Decker, Mathias; Moisse, Matthieu; Robberecht, Wim; Van Den Bosch, Ludo; Van Damme, Philip.
  • Beel S; Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Leuven, Belgium.
  • Herdewyn S; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Fazal R; Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Leuven, Belgium.
  • De Decker M; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Moisse M; Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Leuven, Belgium.
  • Robberecht W; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Van Den Bosch L; Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Leuven, Belgium.
  • Van Damme P; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
Mol Neurodegener ; 13(1): 55, 2018 10 16.
Article en En | MEDLINE | ID: mdl-30326935

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Axones / Proteínas de Unión al ADN / Demencia Frontotemporal / Progranulinas / Esclerosis Amiotrófica Lateral / Mutación Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2018 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Axones / Proteínas de Unión al ADN / Demencia Frontotemporal / Progranulinas / Esclerosis Amiotrófica Lateral / Mutación Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2018 Tipo del documento: Article