[Successful pembrolizumab therapy in metastasized adenosquamous carcinoma of the colon]. / Erfolgreiche Pembrolizumab-Therapie bei metastasiertem adenosquamösem Karzinom des Kolons.
Pathologe
; 40(5): 540-545, 2019 Sep.
Article
en De
| MEDLINE
| ID: mdl-30350176
ABSTRACT
Adenosquamous carcinoma (ASqC) is an exceedingly rare subtype of colorectal cancer without any known special guidelines for treatment. The biological behaviour and molecular background are widely unknown, although a few case studies report a worse prognosis compared to ordinary colorectal adenocarcinoma. We herein report for the first time the successful immune checkpoint inhibitor therapy in a 40-year-old patient suffering from metastasized right-sided colonic ASqC with unique molecular features, after having previously progressed under standard chemotherapy.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Adenocarcinoma
/
Neoplasias del Colon
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Carcinoma Adenoescamoso
/
Anticuerpos Monoclonales Humanizados
Tipo de estudio:
Guideline
Límite:
Adult
/
Humans
Idioma:
De
Año:
2019
Tipo del documento:
Article