Developmental and family history-based analysis of congenital fused labia phenotype in the captive common marmoset (Callithrix jacchus).
J Med Primatol
; 48(1): 43-50, 2019 02.
Article
en En
| MEDLINE
| ID: mdl-30350862
ABSTRACT
BACKGROUND:
Congenital fused labia (CFL) is defined as a failure or significant delay in the opening of the juvenile sealed labia majora. This phenotype is known to be variably common in adult captive female marmosets but has never been investigated in detail before. MATERIALS ANDMETHODS:
Here, we define, describe and quantify the variations in the degree of closure of the vulva in 122 captive marmosets (Callithrix jacchus) from 1.2 to 42 months old and include colony analysis.RESULTS:
There was a negative correlation between the degree of labial fusion and animal age after prepubertal period (P < 0.05). CFL females had higher number CFL relatives (4.3 ± 0.6 vs 2.4 ± 0.5 for non-CFL, P < 0.05) and more external ancestors compared to non-CFL (P < 0.05).CONCLUSIONS:
Our results therefore suggest that CFL phenotype is most likely associated with epigenetic effects induced by the captive environment and colony management strategy of extensive crossing of family lines to promote heterozygosity.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Enfermedades de la Vulva
/
Callithrix
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Enfermedades de los Monos
Límite:
Animals
Idioma:
En
Año:
2019
Tipo del documento:
Article