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De novo NAD+ synthesis enhances mitochondrial function and improves health.
Katsyuba, Elena; Mottis, Adrienne; Zietak, Marika; De Franco, Francesca; van der Velpen, Vera; Gariani, Karim; Ryu, Dongryeol; Cialabrini, Lucia; Matilainen, Olli; Liscio, Paride; Giacchè, Nicola; Stokar-Regenscheit, Nadine; Legouis, David; de Seigneux, Sophie; Ivanisevic, Julijana; Raffaelli, Nadia; Schoonjans, Kristina; Pellicciari, Roberto; Auwerx, Johan.
  • Katsyuba E; Laboratory of Integrative and Systems Physiology, Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Mottis A; Laboratory of Integrative and Systems Physiology, Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Zietak M; Laboratory of Metabolic Signaling, Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • De Franco F; Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland.
  • van der Velpen V; TES Pharma, Loc. Taverne, Corciano, Italy.
  • Gariani K; Metabolomics Platform, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
  • Ryu D; Laboratory of Integrative and Systems Physiology, Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Cialabrini L; Service of Endocrinology, Diabetes, Hypertension and Nutrition, Geneva University Hospitals, Geneva, Switzerland.
  • Matilainen O; Laboratory of Integrative and Systems Physiology, Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Liscio P; Molecular and Integrative Biology Lab, Healthy Aging-Korean Medical Research Center, Department of Korean Medical Science, School of Korean Medicine, Pusan National University, Yangsan, South Korea.
  • Giacchè N; Department of Agricultural, Food and Environmental Sciences, Polytechnic University of Marche, Ancona, Italy.
  • Stokar-Regenscheit N; Laboratory of Integrative and Systems Physiology, Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Legouis D; Institute of Biotechnology, University of Helsinki, Helsinki, Finland.
  • de Seigneux S; TES Pharma, Loc. Taverne, Corciano, Italy.
  • Ivanisevic J; TES Pharma, Loc. Taverne, Corciano, Italy.
  • Raffaelli N; Histology Core Facility, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Schoonjans K; Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche, Basel, Switzerland.
  • Pellicciari R; Intensive Care Unit, Department of Anaesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Geneva, Switzerland.
  • Auwerx J; Laboratory of Nephrology, Department of Internal Medicine Specialties and Department of Cell Physiology and Metabolism, University of Geneva, Geneva, Switzerland.
Nature ; 563(7731): 354-359, 2018 11.
Article en En | MEDLINE | ID: mdl-30356218
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carboxiliasas / Salud / Secuencia Conservada / Evolución Molecular / Mitocondrias / NAD Límite: Animals / Female / Humans / Male Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carboxiliasas / Salud / Secuencia Conservada / Evolución Molecular / Mitocondrias / NAD Límite: Animals / Female / Humans / Male Idioma: En Año: 2018 Tipo del documento: Article