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Type 2 diabetes increases oocyte mtDNA mutations which are eliminated in the offspring by bottleneck effect.
Li, Li; Wu, Chang-Sheng; Hou, Guan-Mei; Dong, Ming-Zhe; Wang, Zhen-Bo; Hou, Yi; Schatten, Heide; Zhang, Gui-Rong; Sun, Qing-Yuan.
  • Li L; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
  • Wu CS; University of Chinese Academy of Sciences, Beijing, 100101, China.
  • Hou GM; Peking Medriv Academy of Genetics and Reproduction, Beijing, 102629, China.
  • Dong MZ; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
  • Wang ZB; College of Life Science, Qingdao Agricultural University, Qingdao, 266109, China.
  • Hou Y; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
  • Schatten H; University of Chinese Academy of Sciences, Beijing, 100101, China.
  • Zhang GR; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
  • Sun QY; University of Chinese Academy of Sciences, Beijing, 100101, China.
Reprod Biol Endocrinol ; 16(1): 110, 2018 Nov 03.
Article en En | MEDLINE | ID: mdl-30390692

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Oocitos / ADN Mitocondrial / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 2 / Mutación Tipo de estudio: Etiology_studies Límite: Animals / Pregnancy Idioma: En Año: 2018 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Oocitos / ADN Mitocondrial / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 2 / Mutación Tipo de estudio: Etiology_studies Límite: Animals / Pregnancy Idioma: En Año: 2018 Tipo del documento: Article