Phenotypic, cytogenetic and molecular characterization of a new B-chronic lymphocytic leukaemia (B-CLL) cell line.
Leuk Res
; 11(7): 579-88, 1987.
Article
en En
| MEDLINE
| ID: mdl-3039258
ABSTRACT
A lymphoid cell line was established from a patient with B-cell chronic lymphocytic leukaemia (B-CLL) by infecting blood lymphocytes with Epstein-Barr virus (EBV). Immunoglobulin gene rearrangement studies and the presence of a chromosome marker (isochromosome 17q) provided the formal proof that the line has originated from the neoplastic B cells. The morphology and phenotype indicate that the EBV-induced cell line has reached a plasma cell-like stage of differentiation.
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Banco de datos:
MEDLINE
Asunto principal:
Células Plasmáticas
/
Leucemia Linfoide
/
Línea Celular
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Año:
1987
Tipo del documento:
Article