Synthesis and biological evaluation of 1,2-disubsubstituted 4-quinolone analogues of <i>Pseudonocardia</i> sp. natural products.

Synthesis and biological evaluation of 1,2-disubsubstituted 4-quinolone analogues of Pseudonocardia sp. natural products.

Geddis, Stephen M; Coroama, Teodora; Forrest, Suzanne; Hodgkinson, James T; Welch, Martin; Spring, David R.

Geddis SM; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.
Coroama T; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.
Forrest S; Department of Biochemistry, University of Cambridge, 80 Tennis Road, Cambridge, CB2 1GA, UK.
Hodgkinson JT; Leicester Institute of Structural and Chemical Biology, and Department of Chemistry, University of Leicester, George Porter Building, University Road, Leicester, LE1 7RH, UK.
Welch M; Department of Biochemistry, University of Cambridge, 80 Tennis Road, Cambridge, CB2 1GA, UK.
Spring DR; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.

Beilstein J Org Chem ; 14: 2680-2688, 2018.

Article en En | MEDLINE | ID: mdl-30410629