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Long-term treatment with the PARP inhibitor niraparib does not increase the mutation load in cell line models and tumour xenografts.
Póti, Ádám; Berta, Kinga; Xiao, Yonghong; Pipek, Orsolya; Klus, Gregory T; Ried, Thomas; Csabai, István; Wilcoxen, Keith; Mikule, Keith; Szallasi, Zoltan; Szüts, Dávid.
  • Póti Á; Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest, Hungary.
  • Berta K; Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest, Hungary.
  • Xiao Y; Tesaro, Waltham, MA, USA.
  • Pipek O; Department of Physics of Complex Systems, Eötvös Loránd University, Budapest, Hungary.
  • Klus GT; Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Ried T; Computational Health Informatics Program (CHIP), Boston Children's Hospital, Boston, MA, USA.
  • Csabai I; Harvard Medical School, Boston, MA, USA.
  • Wilcoxen K; Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Mikule K; Department of Physics of Complex Systems, Eötvös Loránd University, Budapest, Hungary.
  • Szallasi Z; Tesaro, Waltham, MA, USA.
  • Szüts D; Tesaro, Waltham, MA, USA.
Br J Cancer ; 119(11): 1392-1400, 2018 11.
Article en En | MEDLINE | ID: mdl-30425352
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperidinas / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Indazoles / Mutación / Antineoplásicos Límite: Female / Humans Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperidinas / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Indazoles / Mutación / Antineoplásicos Límite: Female / Humans Idioma: En Año: 2018 Tipo del documento: Article