Optical spectroscopic ultrasound displacement imaging.

ABSTRACT

Photoacoustic imaging has been intensively studied in recent years, and many of the achievements have already been applied in important biomedical and clinical applications, e.g. spectroscopic photoacoustic imaging to extract functional and molecular information. However, spectroscopic photoacoustic imaging requires expensive and bulky tunable laser source, which severely hinder its further development towards portable device. In this paper, we propose a novel imaging method, named optical spectroscopic ultrasound displacement (OSUD) imaging, which enables optical spectroscopic imaging in deep scattering tissue using multiple low-cost continuous-wave laser sources and ultrasound imaging equipment. The principle of the OSUD imaging method will be introduced, and followed by preliminary experimental results. The OSUD imaging may provide another pathway to provide spectroscopic optical absorption contrast in deep scattering tissue beyond commonly used photoacoustic imaging.