Overcoming the Undesirable CRISPR-Cas9 Expression in Gene Correction.

Xia, Emily; Duan, Rongqi; Shi, Fushan; Seigel, Kyle E; Grasemann, Hartmut; Hu, Jim.

Xia E; Translational Medicine, Hospital for Sick Children Research Institute, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.
Duan R; Translational Medicine, Hospital for Sick Children Research Institute, 686 Bay Street, Toronto, ON M5G 0A4, Canada.
Shi F; Translational Medicine, Hospital for Sick Children Research Institute, 686 Bay Street, Toronto, ON M5G 0A4, Canada.
Seigel KE; Translational Medicine, Hospital for Sick Children Research Institute, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.
Grasemann H; Translational Medicine, Hospital for Sick Children Research Institute, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Paediatrics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.
Hu J; Translational Medicine, Hospital for Sick Children Research Institute, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada; Department of Paediatrics, University of Toronto, 1 Kin

Mol Ther Nucleic Acids ; 13: 699-709, 2018 Dec 07.

Article en En | MEDLINE | ID: mdl-30513454