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Precision Medicine: Changing the way we think about healthcare.
Gameiro, Gustavo Rosa; Sinkunas, Viktor; Liguori, Gabriel Romero; Auler-Júnior, José Otavio Costa.
  • Gameiro GR; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, BR.
  • Sinkunas V; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, BR.
  • Liguori GR; Laboratorio de Cirurgia Cardiovascular e Fisiopatologia da Circulacao (LIM-11), Instituto do Coração (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.
  • Auler-Júnior JOC; Divisao de Anestesiologia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.
Clinics (Sao Paulo) ; 73: e723, 2018 12 03.
Article en En | MEDLINE | ID: mdl-30517307
ABSTRACT
Health care has changed since the decline in mortality caused by infectious diseases as well as chronic and non-contagious diseases, with a direct impact on the cost of public health and individual health care. We must now transition from traditional reactive medicine based on symptoms, diagnosis and treatment to a system that targets the disease before it occurs and, if it cannot be avoided, treats the disease in a personalized manner. Precision Medicine is that new way of thinking about medicine. In this paper, we performed a thorough review of the literature to present an updated review on the subject, discussing the impact of the use of genetics and genomics in the care process as well as medical education, clinical research and ethical issues. The Precision Medicine model is expanded upon in this article to include its principles of prediction, prevention, personalization and participation. Finally, we discuss Precision Medicine in various specialty fields and how it has been implemented in developing countries and its effects on public health and medical education.
Asunto(s)

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Medicina de Precisión Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Año: 2018 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Medicina de Precisión Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Año: 2018 Tipo del documento: Article