Synthesis and characterization of novel substituted thiophene derivatives and discovery of their carbonic anhydrase and acetylcholinesterase inhibition effects.

Cetin, Adnan; Türkan, Fikret; Taslimi, Parham; Gulçin, Ilhami

Cetin, Adnan; Türkan, Fikret; Taslimi, Parham; Gulçin, Ilhami.

Cetin A; Department of Science, Faculty of Education, Mus Alparslan University, Mus, Turkey.
Türkan F; Health Services Vocational School, Igdir University, Igdir, Turkey.
Taslimi P; Department of Chemistry, Faculty of Science, Ataturk University, Erzurum, Turkey.
Gulçin I; Department of Chemistry, Faculty of Science, Ataturk University, Erzurum, Turkey.

J Biochem Mol Toxicol ; 33(3): e22261, 2019 Mar.

Article en En | MEDLINE | ID: mdl-30537031

Asunto(s)

Acetilcolinesterasa/efectos de los fármacos; Anhidrasa Carbónica II/antagonistas & inhibidores; Anhidrasa Carbónica I/antagonistas & inhibidores; Tiofenos/farmacología; Acetilcolinesterasa/metabolismo; Anhidrasa Carbónica I/metabolismo; Anhidrasa Carbónica II/metabolismo; Inhibidores de Anhidrasa Carbónica/farmacología; Inhibidores de la Colinesterasa/farmacología; Humanos; Cinética; Tiofenos/síntesis química

Palabras clave

acetylcholinesterase; carbonic anhydrase; enzyme inhibition; synthesis; thiophene

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Acetilcolinesterasa / Tiofenos / Anhidrasa Carbónica I / Anhidrasa Carbónica II Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article

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