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Deception through Mimicry: A Cellular Antiviral Strategy.
Wu, Nicholas C; Ward, Andrew B.
  • Wu NC; Department of Integrative Structural and Computational Biology, the Scripps Research Institute, La Jolla, CA 92037, USA.
  • Ward AB; Department of Integrative Structural and Computational Biology, the Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: andrew@scripps.edu.
Cell ; 175(7): 1728-1729, 2018 12 13.
Article en En | MEDLINE | ID: mdl-30550784
ABSTRACT
Viruses use mimicry to hijack cellular machinery, but can human cells use mimicry as an antiviral approach? Batra et al. identify a novel antiviral restriction factor, RBBP6, by characterizing the cellular interactome of Ebola virus. RBBP6 targets the Ebola virus transcription factor VP30 by mimicking the binding of Ebola virus nucleoprotein.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Fiebre Hemorrágica Ebola / Ebolavirus Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Fiebre Hemorrágica Ebola / Ebolavirus Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2018 Tipo del documento: Article