Advanced Methods for Accessing Protein Shape-Shifting Present New Therapeutic Opportunities.

Knoverek, Catherine R; Amarasinghe, Gaya K; Bowman, Gregory R

Knoverek, Catherine R; Amarasinghe, Gaya K; Bowman, Gregory R.

Knoverek CR; Department of Biochemistry & Molecular Biophysics, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.
Amarasinghe GK; Department of Pathology & Immunology, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.
Bowman GR; Department of Biochemistry & Molecular Biophysics, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA. Electronic address: g.bowman@wustl.edu.

Trends Biochem Sci ; 44(4): 351-364, 2019 04.

Article en En | MEDLINE | ID: mdl-30555007

Asunto(s)

Biología Computacional; Proteínas/química; Humanos; Conformación Proteica; Proteínas/metabolismo

Palabras clave

allostery; cryptic pockets; protein dynamics

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas / Biología Computacional Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article

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