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The crystal structure of a tetrahydrofolate-bound dihydrofolate reductase reveals the origin of slow product release.
Cao, Hongnan; Gao, Mu; Zhou, Hongyi; Skolnick, Jeffrey.
  • Cao H; Center for the Study of Systems Biology, School of Biological Sciences, Georgia Institute of Technology, 950 Atlantic Drive, NW, Atlanta, GA 30332 USA.
  • Gao M; Center for the Study of Systems Biology, School of Biological Sciences, Georgia Institute of Technology, 950 Atlantic Drive, NW, Atlanta, GA 30332 USA.
  • Zhou H; Center for the Study of Systems Biology, School of Biological Sciences, Georgia Institute of Technology, 950 Atlantic Drive, NW, Atlanta, GA 30332 USA.
  • Skolnick J; Center for the Study of Systems Biology, School of Biological Sciences, Georgia Institute of Technology, 950 Atlantic Drive, NW, Atlanta, GA 30332 USA.
Commun Biol ; 1: 226, 2018.
Article en En | MEDLINE | ID: mdl-30564747