Inclusion of memory effects in a dynamic model of electroporation in biological tissues.
Artif Organs
; 43(7): 688-693, 2019 Jul.
Article
en En
| MEDLINE
| ID: mdl-30589443
ABSTRACT
This article presents experimental and computational results of electroporation in rat liver. The experiments were performed using different forms of electrodes and waveforms of applied electric pulses. For the numerical simulation, the electroporation model proposed by Ramos and Weinert in a previous publication was used. Dynamic adjustments were used for obtaining a good modeling of the electric current. A single set of model parameters was obtained to fit the simulated current response for different waveforms and electrodes. These parameters were obtained with the use of a genetic algorithm that minimized the error between the simulated and experimental currents. The electroporation model with dynamic adjustment proved to be an appropriate simulation tool to predict the tissue conductivity during stimulation by intense electrical fields.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Simulación por Computador
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Electroporación
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Hígado
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Modelos Biológicos
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Año:
2019
Tipo del documento:
Article