Engineering Bacillus for efficient production of heterologous protein: current progress, challenge and prospect.

Cai, D; Rao, Y; Zhan, Y; Wang, Q; Chen, S

Cai, D; Rao, Y; Zhan, Y; Wang, Q; Chen, S.

Cai D; State Key Laboratory of Biocatalysis and Enzyme Engineering, Environmental Microbial Technology Center of Hubei Province, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, College of Life Sciences, Hubei University, Wuhan, PR China.
Rao Y; State Key Laboratory of Biocatalysis and Enzyme Engineering, Environmental Microbial Technology Center of Hubei Province, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, College of Life Sciences, Hubei University, Wuhan, PR China.
Zhan Y; State Key Laboratory of Biocatalysis and Enzyme Engineering, Environmental Microbial Technology Center of Hubei Province, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, College of Life Sciences, Hubei University, Wuhan, PR China.
Wang Q; State Key Laboratory of Biocatalysis and Enzyme Engineering, Environmental Microbial Technology Center of Hubei Province, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, College of Life Sciences, Hubei University, Wuhan, PR China.
Chen S; State Key Laboratory of Biocatalysis and Enzyme Engineering, Environmental Microbial Technology Center of Hubei Province, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, College of Life Sciences, Hubei University, Wuhan, PR China.

J Appl Microbiol ; 126(6): 1632-1642, 2019 Jun.

Article en En | MEDLINE | ID: mdl-30609144

Asunto(s)

Bacillus/genética; Bacillus/metabolismo; Proteínas Bacterianas/metabolismo; Ingeniería Genética; Microbiología Industrial/tendencias; Bacillus/química; Bacillus/crecimiento & desarrollo; Proteínas Bacterianas/genética; Técnicas de Visualización de Superficie Celular; Regulación Bacteriana de la Expresión Génica; Estabilidad Proteica; Proteínas Recombinantes/genética; Proteínas Recombinantes/metabolismo; Vías Secretoras; Esporas Bacterianas/química; Esporas Bacterianas/genética; Esporas Bacterianas/crecimiento & desarrollo; Esporas Bacterianas/metabolismo

Palabras clave

Bacillus; cell growth; food-grade system; protein stability; secretion pathway; spore surface display; transcriptional regulation

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Bacillus / Proteínas Bacterianas / Microbiología Industrial / Ingeniería Genética Idioma: En Año: 2019 Tipo del documento: Article

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