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Preferential MGMT methylation could predispose a subset of KIT/PDGFRA-WT GISTs, including SDH-deficient ones, to respond to alkylating agents.
Ricci, Riccardo; Martini, Maurizio; Ravegnini, Gloria; Cenci, Tonia; Milione, Massimo; Lanza, Paola; Pierconti, Francesco; Santini, Donatella; Angelini, Sabrina; Biondi, Alberto; Rosa, Fausto; Alfieri, Sergio; Clemente, Gennaro; Persiani, Roberto; Cassano, Alessandra; Pantaleo, Maria A; Larocca, Luigi M.
  • Ricci R; Department of Pathology, Università Cattolica del Sacro Cuore, Largo F.Vito 1, 00168, Rome, Italy. riccardo.ricci@unicatt.it.
  • Martini M; UOC di Anatomia Patologica, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Largo A. Gemelli 8, 00168, Rome, Italy. riccardo.ricci@unicatt.it.
  • Ravegnini G; Department of Pathology, Università Cattolica del Sacro Cuore, Largo F.Vito 1, 00168, Rome, Italy.
  • Cenci T; UOC di Anatomia Patologica, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Largo A. Gemelli 8, 00168, Rome, Italy.
  • Milione M; Department of Pharmacy and Biotechnology, University of Bologna, via Massarenti 9, 40138, Bologna, Italy.
  • Lanza P; UOC di Anatomia Patologica, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Largo A. Gemelli 8, 00168, Rome, Italy.
  • Pierconti F; Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, 20100, Milan, Italy.
  • Santini D; UOC di Anatomia Patologica, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Largo A. Gemelli 8, 00168, Rome, Italy.
  • Angelini S; Department of Pathology, Università Cattolica del Sacro Cuore, Largo F.Vito 1, 00168, Rome, Italy.
  • Biondi A; UOC di Anatomia Patologica, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Largo A. Gemelli 8, 00168, Rome, Italy.
  • Rosa F; Pathology Unit, S.Orsola-Malpighi Hospital, University of Bologna, via Massarenti 9, 40138, Bologna, Italy.
  • Alfieri S; Department of Pharmacy and Biotechnology, University of Bologna, via Massarenti 9, 40138, Bologna, Italy.
  • Clemente G; UOC di Chirurgia Generale, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Largo A. Gemelli 8, 00168, Rome, Italy.
  • Persiani R; UOC di Chirurgia Digestiva, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Largo A. Gemelli 8, 00168, Rome, Italy.
  • Cassano A; UOC di Chirurgia Digestiva, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Largo A. Gemelli 8, 00168, Rome, Italy.
  • Pantaleo MA; Department of Surgery, Università Cattolica del Sacro Cuore, Largo F. Vito 1, 00168, Rome, Italy.
  • Larocca LM; Department of Surgery, Università Cattolica del Sacro Cuore, Largo F. Vito 1, 00168, Rome, Italy.
Clin Epigenetics ; 11(1): 2, 2019 01 07.
Article en En | MEDLINE | ID: mdl-30616628
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Metilasas de Modificación del ADN / Metilación de ADN / Proteínas Supresoras de Tumor / Enzimas Reparadoras del ADN / Tumores del Estroma Gastrointestinal / Neoplasias Gastrointestinales Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Metilasas de Modificación del ADN / Metilación de ADN / Proteínas Supresoras de Tumor / Enzimas Reparadoras del ADN / Tumores del Estroma Gastrointestinal / Neoplasias Gastrointestinales Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2019 Tipo del documento: Article