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Determination of a novel antifibrotic small molecule GDC-3280 in human plasma and urine by liquid chromatography tandem mass spectrometry to support its first-in-human clinical trial.
Wang, Jianshuang; Van Parys, Michael; Pan, Lin; Chen, Yuan; Cheung, Dorothy; McKnight, Janine; Milanowski, Dennis; Ding, Xiao; Dean, Brian.
  • Wang J; Department of Drug Metabolism and Pharmacokinetics, Genentech Inc., South San Francisco, CA, USA.
  • Van Parys M; Department of Bioanalytical Chemistry, Covance Laboratories Inc., Madison, WI, USA.
  • Pan L; Department of Clinical Pharmacology, Genentech Inc, South San Francisco, CA, USA.
  • Chen Y; Department of Drug Metabolism and Pharmacokinetics, Genentech Inc., South San Francisco, CA, USA.
  • Cheung D; Department of Early Clinical Development, Genentech Inc, South San Francisco, CA, USA.
  • McKnight J; Department of Bioanalytical Chemistry, Covance Laboratories Inc., Madison, WI, USA.
  • Milanowski D; Department of Bioanalytical Chemistry, Covance Laboratories Inc., Madison, WI, USA.
  • Ding X; Department of Drug Metabolism and Pharmacokinetics, Genentech Inc., South San Francisco, CA, USA.
  • Dean B; Department of Drug Metabolism and Pharmacokinetics, Genentech Inc., South San Francisco, CA, USA.
Biomed Chromatogr ; 33(4): e4482, 2019 Apr.
Article en En | MEDLINE | ID: mdl-30618197
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piridonas / Cromatografía Liquida / Espectrometría de Masas en Tándem Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Female / Humans / Male Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
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PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piridonas / Cromatografía Liquida / Espectrometría de Masas en Tándem Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Female / Humans / Male Idioma: En Año: 2019 Tipo del documento: Article