The monoclonal antibody CVI-ChNL-68.1 recognizes cells of the monocyte-macrophage lineage in chickens.

Jeurissen, S H; Janse, E M; Koch, G; de Boer, G F

Jeurissen, S H; Janse, E M; Koch, G; de Boer, G F.

Jeurissen SH; Department of Virology, Central Veterinary Institute, Lelystad, The Netherlands.

Dev Comp Immunol ; 12(4): 855-64, 1988.

Article en En | MEDLINE | ID: mdl-3061843

ABSTRACT

ABSTRACT

The characteristics of monoclonal antibody CVI-ChNL-68.1, which specifically reacts with a group of chicken non-lymphoid cells, are described. Both tissue distribution shown on cryostat sections using immuno-enzyme histochemistry, and quantitative data obtained on cell suspensions are presented. Functional characteristics of CVI-ChNL-68.1-positive cells, such as antigen uptake and glass adherence, are determined. Results show that CVI-ChNL-68.1 reacts with monocytes, macrophages, and interdigitating cells. Possible relationships between the various non-lymphoid cells are discussed.

Asunto(s)

Anticuerpos Monoclonales; Células Presentadoras de Antígenos/inmunología; Pollos/inmunología; Macrófagos/inmunología; Monocitos/inmunología; Fosfatasa Ácida/análisis; Animales; Especificidad de Anticuerpos; Antígenos/análisis; Adhesión Celular; Técnicas para Inmunoenzimas; Células de Langerhans; Ratones; Ratones Endogámicos BALB C

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Banco de datos: MEDLINE Asunto principal: Monocitos / Pollos / Macrófagos / Anticuerpos Monoclonales / Células Presentadoras de Antígenos Límite: Animals Idioma: En Año: 1988 Tipo del documento: Article

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