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Cytotoxic CD8+ T lymphocytes expressing ALS-causing SOD1 mutant selectively trigger death of spinal motoneurons.
Coque, Emmanuelle; Salsac, Céline; Espinosa-Carrasco, Gabriel; Varga, Béla; Degauque, Nicolas; Cadoux, Marion; Crabé, Roxane; Virenque, Anaïs; Soulard, Claire; Fierle, Julie K; Brodovitch, Alexandre; Libralato, Margot; Végh, Attila G; Venteo, Stéphanie; Scamps, Frédérique; Boucraut, José; Laplaud, David; Hernandez, Javier; Gergely, Csilla; Vincent, Thierry; Raoul, Cédric.
  • Coque E; The Neuroscience Institute of Montpellier, Inserm UMR1051, University of Montpellier, Saint Eloi Hospital, 34090 Montpellier, France.
  • Salsac C; The Neuroscience Institute of Montpellier, Inserm UMR1051, University of Montpellier, Saint Eloi Hospital, 34090 Montpellier, France.
  • Espinosa-Carrasco G; Inserm U1183, Institute for Regenerative Medicine and Biotherapy, University of Montpellier, 34090 Montpellier, France.
  • Varga B; Charles Coulomb laboratory, L2C, UMR5221, University of Montpellier, CNRS, 34095 Montpellier, France.
  • Degauque N; Centre de Recherche en Transplantation et Immunologie UMR1064, INSERM, Université de Nantes, 44093 Nantes, France.
  • Cadoux M; Institut de Transplantation Urologie Néphrologie (ITUN), University Hospital Centre Nantes, 44093 Nantes, France.
  • Crabé R; Centre de Recherche en Transplantation et Immunologie UMR1064, INSERM, Université de Nantes, 44093 Nantes, France.
  • Virenque A; Institut de Transplantation Urologie Néphrologie (ITUN), University Hospital Centre Nantes, 44093 Nantes, France.
  • Soulard C; The Neuroscience Institute of Montpellier, Inserm UMR1051, University of Montpellier, Saint Eloi Hospital, 34090 Montpellier, France.
  • Fierle JK; The Neuroscience Institute of Montpellier, Inserm UMR1051, University of Montpellier, Saint Eloi Hospital, 34090 Montpellier, France.
  • Brodovitch A; The Neuroscience Institute of Montpellier, Inserm UMR1051, University of Montpellier, Saint Eloi Hospital, 34090 Montpellier, France.
  • Libralato M; Ludwig Institute for Cancer Research, Lausanne University, CH 1015 Lausanne, Switzerland.
  • Végh AG; Referral Centre for ALS and Neuromuscular Diseases, La Timone University Hospital, Aix-Marseille University, 13005 Marseille, France.
  • Venteo S; Immunology Laboratory, Assistance Publique-Hôpitaux de Marseille, Conception Hospital, 13005 Marseille, France.
  • Scamps F; The Neuroscience Institute of Montpellier, Inserm UMR1051, University of Montpellier, Saint Eloi Hospital, 34090 Montpellier, France.
  • Boucraut J; Institute of Biophysics, Biological Research Centre, Hungarian Academy of Sciences, H 6726 Szeged, Hungary.
  • Laplaud D; The Neuroscience Institute of Montpellier, Inserm UMR1051, University of Montpellier, Saint Eloi Hospital, 34090 Montpellier, France.
  • Hernandez J; The Neuroscience Institute of Montpellier, Inserm UMR1051, University of Montpellier, Saint Eloi Hospital, 34090 Montpellier, France.
  • Gergely C; Immunology Laboratory, Assistance Publique-Hôpitaux de Marseille, Conception Hospital, 13005 Marseille, France.
  • Vincent T; Timone Neuroscience Institute, Aix-Marseille University, 13005 Marseille, France.
  • Raoul C; Centre de Recherche en Transplantation et Immunologie UMR1064, INSERM, Université de Nantes, 44093 Nantes, France.
Proc Natl Acad Sci U S A ; 116(6): 2312-2317, 2019 02 05.
Article en En | MEDLINE | ID: mdl-30674678
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T Citotóxicos / Expresión Génica / Superóxido Dismutasa-1 / Esclerosis Amiotrófica Lateral / Neuronas Motoras / Mutación Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T Citotóxicos / Expresión Génica / Superóxido Dismutasa-1 / Esclerosis Amiotrófica Lateral / Neuronas Motoras / Mutación Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Año: 2019 Tipo del documento: Article