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Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial.
Lorentz, Christina U; Verbout, Norah G; Wallisch, Michael; Hagen, Matthew W; Shatzel, Joseph J; Olson, Sven R; Puy, Cristina; Hinds, Monica T; McCarty, Owen J T; Gailani, David; Gruber, András; Tucker, Erik I.
  • Lorentz CU; From Aronora, Inc, Portland, OR (C.U.L., N.G.V., M.W., A.G., E.I.T.).
  • Verbout NG; Department of Biomedical Engineering (C.U.L., N.G.V., M.W., M.W.H., J.J.S., S.R.O., C.P., M.T.H., O.J.T.M., A.G., E.I.T.), Oregon Health & Science University, Portland.
  • Wallisch M; From Aronora, Inc, Portland, OR (C.U.L., N.G.V., M.W., A.G., E.I.T.).
  • Hagen MW; Department of Biomedical Engineering (C.U.L., N.G.V., M.W., M.W.H., J.J.S., S.R.O., C.P., M.T.H., O.J.T.M., A.G., E.I.T.), Oregon Health & Science University, Portland.
  • Shatzel JJ; From Aronora, Inc, Portland, OR (C.U.L., N.G.V., M.W., A.G., E.I.T.).
  • Olson SR; Department of Biomedical Engineering (C.U.L., N.G.V., M.W., M.W.H., J.J.S., S.R.O., C.P., M.T.H., O.J.T.M., A.G., E.I.T.), Oregon Health & Science University, Portland.
  • Puy C; Department of Biomedical Engineering (C.U.L., N.G.V., M.W., M.W.H., J.J.S., S.R.O., C.P., M.T.H., O.J.T.M., A.G., E.I.T.), Oregon Health & Science University, Portland.
  • Hinds MT; Department of Biomedical Engineering (C.U.L., N.G.V., M.W., M.W.H., J.J.S., S.R.O., C.P., M.T.H., O.J.T.M., A.G., E.I.T.), Oregon Health & Science University, Portland.
  • McCarty OJT; Division of Hematology and Medical Oncology (J.J.S., S.R.O., O.J.T.M., A.G.), Oregon Health & Science University, Portland.
  • Gailani D; Department of Biomedical Engineering (C.U.L., N.G.V., M.W., M.W.H., J.J.S., S.R.O., C.P., M.T.H., O.J.T.M., A.G., E.I.T.), Oregon Health & Science University, Portland.
  • Gruber A; Division of Hematology and Medical Oncology (J.J.S., S.R.O., O.J.T.M., A.G.), Oregon Health & Science University, Portland.
  • Tucker EI; Department of Biomedical Engineering (C.U.L., N.G.V., M.W., M.W.H., J.J.S., S.R.O., C.P., M.T.H., O.J.T.M., A.G., E.I.T.), Oregon Health & Science University, Portland.
Arterioscler Thromb Vasc Biol ; 39(4): 799-809, 2019 04.
Article en En | MEDLINE | ID: mdl-30700130
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factor XI / Factor XIa / Anticuerpos Monoclonales Humanizados / Fibrinolíticos / Anticoagulantes Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Animals / Humans Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factor XI / Factor XIa / Anticuerpos Monoclonales Humanizados / Fibrinolíticos / Anticoagulantes Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Animals / Humans Idioma: En Año: 2019 Tipo del documento: Article