Heparin, bivalirudin, or the best of both for STEMI interventions.
Catheter Cardiovasc Interv
; 93(2): 248-249, 2019 02 01.
Article
en En
| MEDLINE
| ID: mdl-30719862
ABSTRACT
Whether heparin, bivalirudin, or bivalirudin delivered on the background of prior heparin therapy, during primary PCI therapy is associated with a better outcome is difficult to ascertain from any one study. Meta-analysis of available trials suggests that the use of bivalirudin on top of prior heparin therapy may be associated with the lowest all-cause mortality and major adverse cardiovascular events while preserving much of the access site bleeding reduction of bivalirudin alone. There may be a role for initial therapy of STEMI with a broad-spectrum anticoagulant such as heparin that is then focused to a more specific direct-thrombin inhibitor (bivalirudin) in primary PCI.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Intervención Coronaria Percutánea
/
Infarto del Miocardio con Elevación del ST
Límite:
Humans
Idioma:
En
Año:
2019
Tipo del documento:
Article