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RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth.
Umesalma, Shaikamjad; Kaemmer, Courtney A; Kohlmeyer, Jordan L; Letney, Blake; Schab, Angela M; Reilly, Jacqueline A; Sheehy, Ryan M; Hagen, Jussara; Tiwari, Nitija; Zhan, Fenghuang; Leidinger, Mariah R; O'Dorisio, Thomas M; Dillon, Joseph; Merrill, Ronald A; Meyerholz, David K; Perl, Abbey L; Brown, Bart J; Braun, Terry A; Scott, Aaron T; Ginader, Timothy; Taghiyev, Agshin F; Zamba, Gideon K; Howe, James R; Strack, Stefan; Bellizzi, Andrew M; Narla, Goutham; Darbro, Benjamin W; Quelle, Frederick W; Quelle, Dawn E.
  • Umesalma S; Department of Pharmacology.
  • Kaemmer CA; Department of Pharmacology.
  • Kohlmeyer JL; Molecular Medicine Graduate Program.
  • Letney B; Department of Pharmacology.
  • Schab AM; Department of Pharmacology.
  • Reilly JA; Department of Pharmacology.
  • Sheehy RM; Department of Pharmacology.
  • Hagen J; Free Radical & Radiation Biology Training Program.
  • Tiwari N; Department of Pharmacology.
  • Zhan F; Department of Pharmacology.
  • Leidinger MR; Department of Internal Medicine, and.
  • O'Dorisio TM; Department of Pathology, in the College of Medicine, Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa, USA.
  • Dillon J; Department of Internal Medicine, and.
  • Merrill RA; Department of Internal Medicine, and.
  • Meyerholz DK; Department of Pharmacology.
  • Perl AL; Department of Pathology, in the College of Medicine, Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa, USA.
  • Brown BJ; Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, USA.
  • Braun TA; Departments of Biomedical Engineering.
  • Scott AT; Departments of Biomedical Engineering.
  • Ginader T; Surgery.
  • Taghiyev AF; Biostatistics, and.
  • Zamba GK; Pediatrics, Colleges of Medicine, Engineering, or Public Health, University of Iowa, Iowa City, Iowa, USA.
  • Howe JR; Biostatistics, and.
  • Strack S; Surgery.
  • Bellizzi AM; Department of Pharmacology.
  • Narla G; Department of Pathology, in the College of Medicine, Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa, USA.
  • Darbro BW; Department of Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Quelle FW; Pediatrics, Colleges of Medicine, Engineering, or Public Health, University of Iowa, Iowa City, Iowa, USA.
  • Quelle DE; Department of Pharmacology.
J Clin Invest ; 129(4): 1641-1653, 2019 03 04.
Article en En | MEDLINE | ID: mdl-30721156
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Transducción de Señal / Proteínas Oncogénicas / Carcinoma Neuroendocrino / Proteínas de Unión al GTP rab / Proteínas Supresoras de Tumor / Proteínas Proto-Oncogénicas c-akt Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Transducción de Señal / Proteínas Oncogénicas / Carcinoma Neuroendocrino / Proteínas de Unión al GTP rab / Proteínas Supresoras de Tumor / Proteínas Proto-Oncogénicas c-akt Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article