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Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade.
Pai, Chien-Chun Steven; Huang, John T; Lu, Xiaoqing; Simons, Donald M; Park, Chanhyuk; Chang, Anthony; Tamaki, Whitney; Liu, Eric; Roybal, Kole T; Seagal, Jane; Chen, Mingyi; Hagihara, Katsunobu; Wei, Xiao X; DuPage, Michel; Kwek, Serena S; Oh, David Y; Daud, Adil; Tsai, Katy K; Wu, Clint; Zhang, Li; Fasso, Marcella; Sachidanandam, Ravi; Jayaprakash, Anitha; Lin, Ingrid; Casbon, Amy-Jo; Kinsbury, Gillian A; Fong, Lawrence.
  • Pai CS; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Huang JT; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Lu X; AbbVie Bioresearch Center, 100 Research Drive, Worcester, MA 01605, USA.
  • Simons DM; AbbVie Bioresearch Center, 100 Research Drive, Worcester, MA 01605, USA.
  • Park C; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Chang A; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Tamaki W; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Liu E; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Roybal KT; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Seagal J; AbbVie Bioresearch Center, 100 Research Drive, Worcester, MA 01605, USA.
  • Chen M; Department of Hematopathology, School of Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Hagihara K; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Wei XX; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA.
  • DuPage M; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Kwek SS; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Oh DY; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Daud A; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Tsai KK; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Wu C; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Zhang L; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Fasso M; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Sachidanandam R; Girihlet, 355 30th Street, Oakland, CA 94609, USA.
  • Jayaprakash A; Girihlet, 355 30th Street, Oakland, CA 94609, USA.
  • Lin I; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Casbon AJ; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Kinsbury GA; AbbVie Bioresearch Center, 100 Research Drive, Worcester, MA 01605, USA.
  • Fong L; Department of Hematology and Oncology, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: lawrence.fong@ucsf.edu.
Immunity ; 50(2): 477-492.e8, 2019 02 19.
Article en En | MEDLINE | ID: mdl-30737146
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T / Interferón gamma / Resistencia a Antineoplásicos / Antígeno CTLA-4 / Receptor de Muerte Celular Programada 1 / Anticuerpos Monoclonales / Neoplasias Experimentales Límite: Animals / Humans / Male Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T / Interferón gamma / Resistencia a Antineoplásicos / Antígeno CTLA-4 / Receptor de Muerte Celular Programada 1 / Anticuerpos Monoclonales / Neoplasias Experimentales Límite: Animals / Humans / Male Idioma: En Año: 2019 Tipo del documento: Article